GDA STACK
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GDA-STACK
- Glucose Disposal & Nutrient Partitioner
- Insulin Mimetic & Maintain Insulin Sensitivity
- Science led improvements body composition
- Enhanced muscle growth with concomitant fat loss
- Fuller, harder and more vascular look
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GDA STACKâ„¢ - Natural Muscle Builder
- NutriJa® GDA STACK™ combines 12 innovative Glucose Disposal Agent (GDA) ingredients which aims to improve muscle insulin sensitivity and optimise nutrient handling leading to more amino acids and glycogen being directed to muscle cells. By better harnessing the power of insulin you not only effect greater gains in muscle recovery and muscle fullness but also a reduction in bodyfat. As such, GDA STACK™ is a supplement which stands out as one of a rare type which is equally effective regardless of if your primary goal is to build muscle and strength or if it is to boost fat loss while retaining the maximum amount of muscle.
- GDA STACKâ„¢ can be used during both bulking and cutting phases since regardless of your current goal it will help support gains in lean body mass and fat loss. Of course, if you are using it when dieting you would see faster gains in fat loss compared to muscle gains but its mechanism of action is uniquely capable of supporting your physique goals at any time and for this reason it is best used on an ongoing basis to gradually shift your body over time to a leaner, more muscular one.
- GDA STACKâ„¢ is suitable for both men and women looking for a product that improve their physique and does so naturally without any negative side effects.
- Berberine is a fascinating plant that has been documented to possess a wide range of abilities, particularly in regards to its anti-inflammatory and antidiabetic properties.* The compound has been noted in research to enhance glucose uptake into skeletal muscle via AMPK activation.*[15,16] Note: AMPK (5' adenosine monophosphate-activated protein kinase) is an enzyme that plays a key role in cellular energy balance, and activation of AMPK may increase mitochondrial biogenesis in skeletal muscle cells, reduce fat storage, and improve insulin sensitivity.*[17,18,19] Interestingly enough, berberine also has some data noting it may be able to stimulate glucose uptake into muscle cells by itself even if the cell happens to be insulin resistant.*[20]
- Chromium is a trace mineral essential to a number of important functions in the body, including cholesterol synthesis and insulin metabolism.*[1,2] Basically, insulin requires chromium in order to function properly, and without adequate chromium stores, insulin metabolism suffers as does the uptake and utilization of glucose, amino acids, and fats. This means that protein synthesis may be stunted, hindering muscle recovery and growth* Research also has shown a link between individuals with type 2 diabetes having lower blood levels of chromium than those without the disease.*[1,2]
- Gymnema Sylvestre is a herb native to the central and southern forests of India and Sri Lanka. Also known as cowplant, gymnema has been extensively used in eastern medicine to help support insulin function and reduce diabetes risk.*[5] Better insulin function promotes stable blood sugar levels, and helps shuttle glucose into skeletal muscles where it can then be used to support energy production and athletic performance.* A comprehensive review of gymnema sylvestre noted it may also help reduce plasma glucose, leptin levels, body weight and even BMI (body mass index).*[6]
- Banaba, a.k.a. Lagerstroemia, is a well-known plant, largely due to its antidiabetic properties.* The leaves of the banaba plant are rich in a compound known as corosolic acid, which is believed to induce GLUT4 translocation and subsequently support glucose control.[7,8] In case you weren’t aware, GLUT4 is the insulin-responsive glucose transporter gene in the body. Research has shown that a malfunctioning GLUT4 gene may cause insulin resistance in skeletal muscle as well as diabetes.[9]* Corosolic acid inhibits enzymatic activities of several diabetes-related non-receptor protein tyrosine phosphatases, including PTP1B, which can activate insulin receptor B phosphorylation, making it a viable option for combatting symptoms associated with obesity and diabetes.* Research also finds that corosolic acid supports glycolysis and reduces gluconeogenesis[10]. Some research has even shown it’s beneficial for weight loss too, via inhibition of pancreatic lipase enzyme (the enzyme responsible for fat absorption).*[11] Finally, banaba leaf also has research noting that it may enhance insulin sensitivity and glucose transport, allowing greater glucose control and utilization.*[12,13,14]
- Cinnamon is an incredibly popular culinary spice that also exerts a wide range of beneficial biological effects. Research notes that cinnamon may help reduce the rate at which glucose enters the body as well as improve glucose utilization within cells.[21] Additional studies indicate that cinnamon may help lower blood sugar spikes, fasting glucose and cholesterol levels.[22] Various phenolic compounds within cinnamon, such as catechin, epicatechin, and procyanidin have been noted to inhibit the formation of advanced glycation end products.*[21]
- Alpha-lipoic acid is a compound found naturally inside every cell of the human body. Its primary role is to convert blood sugar (glucose) into energy using oxygen, a process referred to as aerobic metabolism. Research notes that alpha lipoic acid (ALA) may help reduce fasting blood sugar], suppress appetite, and increase energy expenditure.*[23,24,25]
- Bitter melon is linked to lowering the body’s blood sugar. This is because the bitter melon has properties that act like insulin, which helps bring glucose into the cells for energy. The consumption of bitter melon can help your cells utilize glucose and move it to your liver, muscles, and fat. The melon may also be able to help your body retain nutrients by blocking their conversion to glucose that ends up in your blood stream.
- In research Cissus Quandrangularis significantly decreased body weight and belly fat, regardless of diet. It also improved fasting blood sugar, triglycerides, and total and LDL (bad) cholesterol levels. In another 10-week study, 72 people took 300 mg of Cissus quadrangularis daily. Researchers observed that it reduced body weight, body fat, waist size, blood sugar, and total and LDL (bad) cholesterol levels
- Fenugreek Extract help improve how the body uses sugar and increases the amount of insulin released.
- Panax Ginseng Extract has been shown to improve glucose tolerance and insulin resistance in several human studies. Ginseng improves your cells response to and increase your body’s secretion of insulin.
- Amylase is a digestive enzyme responsible for the breaking of the bonds in starches, polysaccharides, and complex carbohydrates into easier to absorb simple sugars. Scientific studies show the ability of this digestive enzyme to maintain normal blood sugar levels and help treat or reverse insulin resistance symptoms.
- A scientific review: the role of chromium in insulin resistance. Diabetes Educ. 2004;Suppl:2-14.
- Hua Y, Clark S, Ren J, Sreejayan N. Molecular Mechanisms of Chromium in Alleviating Insulin Resistance. The Journal of Nutritional Biochemistry. 2012;23(4):313-319. doi:10.1016/j.jnutbio.2011.11.001.
- Juan A. Cooper, Bryan F. Anderson, Paul D. Buckley, Leonard F. Blackwell; Structure and biological activity of nitrogen and oxygen coordinated nicotinic acid complexes of chromium; Inorganica Chimica Acta; Volume 91, Issue 1, January 1984, Pages 1–9
- K. L. Olin, D. M. Stearns, W. H. Armstrong, C. L. Keen; Comparative retention/absorption of 51chromium (51Cr) from 51Cr chloride, 51Cr nicotinate and 51Cr picolinate in a rat model; Trace Elements and Electrolytes; 1994; 182-186;
- Kanetkar P, Singhal R, Kamat M. Gymnema sylvestre: A Memoir. Journal of Clinical Biochemistry and Nutrition. 2007;41(2):77-81. doi:10.3164/jcbn.2007010.
- Pothuraju, R., Sharma, R. K., Chagalamarri, J., Jangra, S. and Kumar Kavadi, P. (2014), A systematic review of Gymnema sylvestre in obesity and diabetes management. J. Sci. Food Agric., 94: 834–840. doi: 10.1002/jsfa.6458.
- Miura T, Itoh Y, Kaneko T, et al. Corosolic acid induces GLUT4 translocation in genetically type 2 diabetic mice. Biol Pharm Bull. 2004;27(7):1103-1105.
- Stenbit AE, Tsao T-S, Li J, et al. GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes. Nat Med. 1997;3:1096. http://dx.doi.org/10.1038/nm1097-1096.
- Pei Z, Liu G, Lubben TH, Szczepankiewicz BG. Inhibition of protein tyrosine phosphatase 1B as a potential treatment of diabetes and obesity. Curr Pharm Des. 2004;10(28):3481-3504.
- Zhang Z-Y, Lee S-Y. PTP1B inhibitors as potential therapeutics in the treatment of Type 2 diabetes and obesity. Expert Opin Investig Drugs. 2003;12(2):223-233. doi:10.1517/13543784.12.2.223.
- Yamada K, Hosokawa M, Fujimoto S, et al. Effect of corosolic acid on gluconeogenesis in rat liver. Diabetes Res Clin Pract. 2008;80(1):48-55. doi:https://doi.org/10.1016/j.diabres.2007.11.011.
- Takagi S, et al; Effect of corosolic acid on dietary hypercholesterolemia and hepatic steatosis in KK-Ay diabetic mice . Biomed Res. (2010)
- Miura T, Takagi S, Ishida T; Management of Diabetes and Its Complications with Banaba (Lagerstroemia speciosa L.) and Corosolic Acid . Evid Based Complement Alternat Med. (2012)
- Judy WV, et al; Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study . J Ethnopharmacol. (2003)
- Yin J, Xing H, Ye J. Efficacy of Berberine in Patients with Type 2 Diabetes. Metabolism: clinical and experimental. 2008;57(5):712-717. doi:10.1016/j.metabol.2008.01.013.
- Lin W, Huang X, Zhang L, Chen D, Wang D, Peng Q, et al. (2012) BMS309403 Stimulates Glucose Uptake in Myotubes through Activation of AMP-Activated Protein Kinase. PLoS ONE7(8): e44570. https://doi.org/10.1371/journal.pone.0044570
- Dong H, Wang N, Zhao L, Lu F. Berberine in the Treatment of Type 2 Diabetes Mellitus: A Systemic Review and Meta-Analysis. Evidence-based Complementary and Alternative Medicine : eCAM. 2012;2012:591654. doi:10.1155/2012/591654.
- Godugu C, Patel AR, Doddapaneni R, Somagoni J, Singh M (2014) Approaches to Improve the Oral Bioavailability and Effects of Novel Anticancer Drugs Berberine and Betulinic Acid. PLoS ONE 9(3): e89919. https://doi.org/10.1371/journal.pone.0089919.
- Bustanji Y, Taha MO, Yousef A-M, Al-Bakri AG. Berberine potently inhibits protein tyrosine phosphatase 1B: investigation by docking simulation and experimental validation. J Enzyme Inhib Med Chem. 2006;21(2):163-171. doi:10.1080/14756360500533026.
- Liu L-Z, Cheung SCK, Lan L-L, et al. Berberine modulates insulin signaling transduction in insulin-resistant cells. Mol Cell Endocrinol. 2010;317(1-2):148-153. doi:10.1016/j.mce.2009.12.027.
- Qin B, Panickar KS, Anderson RA. Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes. J Diabetes Sci Technol. 2010;4(3):685-693. Published 2010 May 1. doi:10.1177/193229681000400324
- Khan, A., Safdar, M., Ali Khan, M. M., Khattak, K. N., & Anderson, R. A. (2003). Cinnamon Improves Glucose and Lipids of People With Type 2 Diabetes. Diabetes Care, 26(12), 3215 LP – 3218. https://doi.org/10.2337/diacare.26.12.3215
- Ansar H, Mazloom Z, Kazemi F, Hejazi N. Effect of alpha-lipoic acid on blood glucose, insulin resistance and glutathione peroxidase of type 2 diabetic patients. Saudi Med J. 2011;32(6):584-588.
- Kim MS, et al; Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase . Nat Med. (2004)
- Cheng PY, et al; Reciprocal effects of α-lipoic acid on adenosine monophosphate-activated protein kinase activity in obesity induced by ovariectomy in rats . Menopause. (2011)
- https://nulivscience.com/ingredients/astragin
WHY
WHEN
WHO
GDA STACK™ INGREDIENTS?
Super Berberine (Berberine cyclodextrin) - 500mg
Chromium - 500mcg
Gymnema Sylvestre - 400mg
Banaba Extract 2% - 100mg
Cinnamon - 400mg
R-ALA - 300mg
Bitter Melon Extract
Cissus Quandrangularis - 250mg
Fenugreek Extract - 250mg
Panax Ginseng Extract - 100mg
Amylase - 200mg
REFERENCES
| Short Description |
|
|---|---|
| Brand | NutriJa™ |
| Ingredients | See Supplement Facts |
| Form | Capsule |
| Product Code/UPC | 720444438534 |
| Item Returns | This item can be returned |
* You can add as many custom tabs as you need!
| Size | Bust (cm) | Waist (cm) | Hip (cm) |
|---|---|---|---|
| XS | 82,5 | 62 | 87,5 |
| S | 85 | 63,5 | 89 |
| M | 87,5 | 67,5 | 93 |
| L | 90 | 72,5 | 98 |
| XL | 93 | 77,5 | 103 |
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